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KMID : 0984720090410040230
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Infection and Chemotherapy
2009 Volume.41 No. 4 p.230 ~ p.232
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Primary Anti-retroviral Resistance in Treatment-naive HIV-infected Patients: A Korean HIV/AIDS Cohort Study
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Song Joon-Young
Cheong Hee-Jin
Lee Jin-Soo
Chung Moon-Hyun
Kim Woo-Joo
Eom Joong-Sik
Jeong Hye-Won
Choi Hee-Jung
Lee Jin-Seo
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Abstract
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Primary anti-retroviral resistance is considered one of the major problems of HIV treatment. Contrary to reports from western countries, prior Korean studies have reported a relatively low primary resistance rate (less than 5%). Based on Korean HIV/AIDS cohort data, we estimated the primary resistance rate among treatment-nave HIV- infected patients. According to the results, the primary resistance rate was higher (8.8%) than reported previously in Korean studies. However, the major PI mutation was not found.
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KEYWORD
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HIV, Antiretroviral therapy, Drug resistance
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